Improved accuracy of cytodiagnosis using the Kato self-collection devise: the usefulness of smear preparation in liquid-based cytology methods

Asian Pac J Cancer Prev. 2012;13(9):4521-4. doi: 10.7314/apjcp.2012.13.9.4521.

Abstract

Object: In the present study, we compared the positive cytodiagnostic test rates with discrepancies using self-collection devices for cervical cancer screening. We made this survey to examine whether or not our self- smear preparation method using the Kato self-collection device contributed to an improved rate of detecting atypical cells compared with existing recommended preparation methods.

Methods: Specimens were collected at 14 facilities handling self-collection methods, and samples were collected by a physician in 2 facilities. The chi- squared test was performed using the SPSS ver. 20 statistical software to determine the relationships between the positive cytodiagnostic rate, specimen preparation methods, and self-collection devices.

Results: Collecting cells using the Kato self-collection device and preparing liquid-based specimens, we obtained a significantly higher rate of positive cytodiagnosis and our results were equal to those obtained with the direct method.

Conclusions: Taking into consideration increased needs for screening using the self-collection method in future, with even more improved test accuracy, a screening test that is acceptable to society needs to be established.

Publication types

  • Comparative Study

MeSH terms

  • Chi-Square Distribution
  • Early Detection of Cancer*
  • Female
  • Humans
  • Self Care / instrumentation
  • Specimen Handling / instrumentation*
  • Specimen Handling / methods
  • Uterine Cervical Dysplasia / diagnosis*
  • Uterine Cervical Neoplasms / diagnosis*
  • Vaginal Smears / instrumentation*
  • Vaginal Smears / standards