The impact of percutaneous coronary intervention on ischemic mitral regurgitation

J Heart Valve Dis. 2012 Sep;21(5):564-9.

Abstract

Background and aim of the study: The study aim was to determine if significant ischemic mitral regurgitation (IMR) is adequately addressed in patients undergoing multi-vessel percutaneous coronary intervention (PCI).

Methods: The cardiac catheterization laboratory database at the authors' institution was accessed over a five-year interval to identify those patients who had undergone multi-vessel PCI. Both, pre- and post-revascularization echocardiographic data were retrieved, and clinical data, MR presence and severity, and outcomes were each assessed.

Results: In total, 150 patients (100 males, 50 females; mean age 63 +/- 12 years) underwent PCI. Of these 150 patients, pre-procedural echocardiograms were not performed in 54 cases (35%); hence, the study group comprised 96 patients with both pre- and postprocedural echocardiograms. Of these patients, 21 (22%) had moderate or greater (2+) IMR. The severity of the IMR did not change significantly after multivessel PCI (2 +/- 0.8+ preoperatively versus 1.9 +/- 1.0+ postoperatively).

Conclusion: Clinically significant IMR occurred not infrequently among patients treated with multivessel PCI, but the severity did not change with percutaneous revascularization, despite this being predominantly complete. In more than one-third of the patients, adequate pre-PCI echocardiography was unavailable, which suggested the possibility that not all IMR had been identified.

MeSH terms

  • Aged
  • Coronary Artery Disease / complications*
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / surgery
  • Echocardiography
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mitral Valve Insufficiency / complications
  • Mitral Valve Insufficiency / diagnostic imaging
  • Mitral Valve Insufficiency / surgery*
  • Percutaneous Coronary Intervention*
  • Retrospective Studies