Simultaneous photoacoustic and optically mediated ultrasound microscopy: phantom study

Opt Lett. 2012 Nov 15;37(22):4606-8. doi: 10.1364/ol.37.004606.

Abstract

An experimental setup for combined photoacoustic (PA) and optically mediated ultrasound (US) microscopy is presented. A spherically focused 35 MHz polyvinylidene fluoride (PVDF) ultrasonic detector with a numerical aperture of 0.28, a focal distance of 9 mm, and a bandwidth (-6 dB level) of 24 MHz was used to obtain PA and US data with a 3 mm imaging depth. A fiber-optic system was employed to deliver laser excitation pulses from a tunable laser to the studied medium. A single optical pulse was used to form both PA and US A-scans. The probing US pulses were generated thermoelastically due to absorption of backscattered laser radiation by the metalized surface of a PVDF film.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Agar
  • Microscopy / instrumentation*
  • Optical Devices*
  • Phantoms, Imaging*
  • Photoacoustic Techniques*
  • Time Factors
  • Ultrasonics*

Substances

  • Agar