Abstract
We report an unusual face selective reduction of the exocyclic double bond in the α-methylene-γ-butyrolactone motif of spiro-oxindole systems. The spiro-oxindoles were assembled by an indium metal mediated Barbier-type reaction followed by an acid catalyzed lactonization.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Indium / chemistry
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Isatin / chemistry*
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Lactones / chemistry*
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Magnetic Resonance Spectroscopy
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Molecular Conformation
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Oxidation-Reduction
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Spiro Compounds / chemistry*
Substances
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Lactones
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Spiro Compounds
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Indium
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Isatin