Acute ischemic cholecystitis after transarterial chemoembolization with drug-eluting beads

Clin Imaging. 2012 Nov-Dec;36(6):861-4. doi: 10.1016/j.clinimag.2012.01.030. Epub 2012 Jun 8.

Abstract

Transarterial chemoembolization (TACE) is a widely used treatment choice for hepatocellular cancer. DC Bead microspheres are a new embolic material for TACE that doxorubicin can be loaded to. The tumor response rate of this well-tolerated treatment was changed between 60% and 81.8%. We report a case of ischemic cholecystitis after TACE with drug-eluting beads (DEB) that required cholecystectomy. The possibility of cholecystitis is always remembered during TACE-DEB for tumors in segment IV and/or V. Although selective catheterization is related with a lower risk for ischemic cholecystitis, the anatomic and vascular variability in patients with malignancy may lead to some unexpected conditions.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / adverse effects
  • Chemoembolization, Therapeutic / adverse effects*
  • Cholecystitis, Acute / chemically induced*
  • Cholecystitis, Acute / diagnostic imaging*
  • Cholecystography*
  • Delayed-Action Preparations / adverse effects
  • Doxorubicin / adverse effects*
  • Gallbladder / blood supply*
  • Gallbladder / drug effects
  • Hemostatics / adverse effects*
  • Humans
  • Male
  • Microspheres
  • Young Adult

Substances

  • Antineoplastic Agents
  • Delayed-Action Preparations
  • Hemostatics
  • Doxorubicin