Abstract
Steroids, a widespread class of natural organic compounds occurring in animals, plants and fungi, have shown great therapeutic value for a broad array of pathologies. The present overview is focused on the anticancer activity of steroids, which is very representative of a rich structural molecular diversity and ability to interact with various biological targets and pathways. This review encompasses the most relevant discoveries on steroid anticancer drugs and leads through the last decade and comprises 668 references.
MeSH terms
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Animals
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Antineoplastic Agents* / chemical synthesis
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Antineoplastic Agents* / chemistry
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Antineoplastic Agents* / isolation & purification
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Antineoplastic Agents* / pharmacology
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Biological Products* / chemical synthesis
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Biological Products* / chemistry
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Biological Products* / isolation & purification
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Biological Products* / pharmacology
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Fungi
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Humans
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Molecular Structure
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Plants, Medicinal
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Steroids* / chemical synthesis
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Steroids* / chemistry
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Steroids* / isolation & purification
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Steroids* / pharmacology
Substances
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Antineoplastic Agents
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Biological Products
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Steroids