Abstract
The synthesis of monofluoroalkenes using an S(N)2' reaction of lithium amides derived from aromatic amines or lithium thiolates with 3,3-difluoropropenes is reported. This transformation features the use of fluoride as a leaving group.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkenes / chemical synthesis*
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Alkenes / chemistry*
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Amides / chemistry*
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Combinatorial Chemistry Techniques
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Hydrocarbons, Fluorinated / chemical synthesis*
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Hydrocarbons, Fluorinated / chemistry*
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Lithium / chemistry*
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Molecular Structure
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Organometallic Compounds / chemistry*
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Sulfhydryl Compounds / chemistry*
Substances
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Alkenes
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Amides
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Hydrocarbons, Fluorinated
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Organometallic Compounds
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Sulfhydryl Compounds
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Lithium