Abstract
The aim of this work was a detailed study of questions connected with the peculiarities of circadian blood pressure profile, efficiency of amlodipine in elderly patients with gout and arterial hypertension. We used 24-hour blood pressure monitoring before and after 3 and 6-months treatment. Patients with gout showed the disturbances of circadian blood pressure profile. Prolonged calcium antagonists are the best drugs for the hypertensive patients with gout.
Publication types
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Clinical Trial
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English Abstract
MeSH terms
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Aged
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Amlodipine* / administration & dosage
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Amlodipine* / adverse effects
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Blood Pressure / drug effects*
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Blood Pressure Monitoring, Ambulatory / methods
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Calcium Channel Blockers / administration & dosage
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Calcium Channel Blockers / adverse effects
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Circadian Rhythm*
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Delayed-Action Preparations / administration & dosage
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Delayed-Action Preparations / adverse effects
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Dose-Response Relationship, Drug
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Drug Monitoring / methods
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Female
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Gout* / complications
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Gout* / diagnosis
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Gout* / physiopathology
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Humans
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Hypertension* / complications
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Hypertension* / diagnosis
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Hypertension* / drug therapy
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Hypertension* / physiopathology
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Male
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Middle Aged
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Treatment Outcome
Substances
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Calcium Channel Blockers
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Delayed-Action Preparations
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Amlodipine