A multi-parameter decoupling method with a Lamb wave sensor for improving the selectivity of label-free liquid detection

Sensors (Basel). 2012;12(8):10369-80. doi: 10.3390/s120810369. Epub 2012 Jul 31.

Abstract

In this paper, a liquid multi-parameter decoupling method with only one Lamb wave sensor is presented. In a Lamb wave sensor, antisymmetric modes (A(01) mode for low frequency, A(03) mode for high frequency) and symmetric modes (S(0) mode) are used to detect multiple parameters of a liquid, such as its density, sound velocity, and viscosity. We found they can play very different roles in the detections. For example, the A(01) mode is very sensitive to the liquid's density but the A(03) mode is sensitive to the sound velocity. Here, the A(0) mode is used to identify the density of the detected liquid and with this density value we obtained the viscosity by the amplitude shifts of the S(0) mode. This could be a way to distinguish an unknown liquid with high sensitivity or to solve the problem of selectivity of label-free detection on biosensors.

Keywords: Lamb wave sensor; density; determination of multi-parameters; sound velocity; viscosity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acoustics / instrumentation*
  • Biosensing Techniques / instrumentation
  • Bromides / chemistry
  • Chemistry Techniques, Analytical / instrumentation*
  • Chemistry Techniques, Analytical / methods
  • Electronics
  • Microtechnology / instrumentation
  • Signal Processing, Computer-Assisted*
  • Sodium Chloride / chemistry
  • Sodium Compounds / chemistry
  • Solutions / analysis
  • Solutions / chemistry*
  • Sound
  • Viscosity

Substances

  • Bromides
  • Sodium Compounds
  • Solutions
  • Sodium Chloride
  • sodium bromide