High-density lipoprotein cholesterol and intracoronary thrombosis burden

Coron Artery Dis. 2013 Jan;24(1):1-5. doi: 10.1097/MCA.0b013e32835aab80.

Abstract

Objective: To carry out a retrospective analysis of the correlation between high-density lipoprotein cholesterol (HDL-C) and intracoronary thrombus burden.

Methods and results: A total of 270 patients with ST-segment elevation myocardial infarction undergoing primary PCI were analyzed retrospectively. They were divided into two groups: patients with (group A, n=111) and patients without (group B, n=159) angiographic characteristics of thrombus. The results showed that the level of HDL-C was markedly lower in group A than that in group B. The logistic regression analysis of the relationship between multiple factors showed that only the level of HDL-C was correlated negatively with the angiographic characteristics of thrombus.

Conclusion: HDL-C is correlated with the angiographic presence of thrombus.

MeSH terms

  • Aged
  • Biomarkers / blood
  • Chi-Square Distribution
  • Cholesterol, HDL / blood*
  • Coronary Angiography*
  • Coronary Thrombosis / blood*
  • Coronary Thrombosis / diagnostic imaging*
  • Coronary Thrombosis / therapy
  • Down-Regulation
  • Female
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Myocardial Infarction / blood
  • Myocardial Infarction / diagnostic imaging
  • Myocardial Infarction / therapy
  • Percutaneous Coronary Intervention
  • Predictive Value of Tests
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index

Substances

  • Biomarkers
  • Cholesterol, HDL