Prevalence of β-hemolytic Streptococcus in children with special health care needs

Braz J Otorhinolaryngol. 2012 Oct;78(5):110-5. doi: 10.5935/1808-8694.20120017.
[Article in English, Portuguese]

Abstract

Pharyngotonsillitis by β-hemolytic Streptococcus mostly affects children and immunocompromised, being Streptococcus pyogenes (Group A) the most common agent in bacterial pharyngotonsillitis.

Aim: This work targeted the research of β-hemolytic Streptococcus Group-A (SBHGA) and No-A (SBHGNA) in the oropharynx of individuals with special health needs from the APAE (Maceió-AL).

Method: A prospective study with oropharynx samples from patients with Down syndrome and other mental disorders (test) and students from a private school (control) aged 5-15 years. Cultures in blood agar (5%) were identified through Gram/catalase tests and bacitracin/trimethoprim-sulfamethoxazole disk diffusion method, applying the chi-squared statistical analysis.

Results: A total of 222 bacterial colonies were isolated in 74 individuals from APAE and 65 in the control group. In the test group, previous episodes of pharyngotonsillitis were reported by 36.49% (27/74) and 9.46% (7/74) were diagnosed with symptoms and/or signs suggestive of oropharynx infection. No positive sample of S. pyogenes was confirmed at APAE, being all samples classified as SBHGNA, with 5 SBHGA in the control group.

Conclusion: The early identification of β-hemolytic Streptococcus is important for the fast treatment of pharyngotonsillitis and the absence of S. pyogenes avoid future suppurative or not-suppurative sequels in the group from APAE.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Case-Control Studies
  • Child
  • Disk Diffusion Antimicrobial Tests
  • Female
  • Humans
  • Intellectual Disability / microbiology*
  • Male
  • Pharyngitis / microbiology*
  • Prevalence
  • Prospective Studies
  • Streptococcal Infections / diagnosis
  • Streptococcal Infections / microbiology*
  • Streptococcus pyogenes / drug effects
  • Streptococcus pyogenes / isolation & purification*
  • Tonsillitis / microbiology*
  • Trimethoprim, Sulfamethoxazole Drug Combination / pharmacology

Substances

  • Anti-Bacterial Agents
  • Trimethoprim, Sulfamethoxazole Drug Combination