Abstract
Modes of transport: A leucine-zipper-tagged GFP was transported into cells by "zipping" it (red) to it's complementary leucine zipper (blue) functionalized with a cell-penetrating peptide (CPP). This transport system has an inherent modularity as the CPP is "clicked" to the leucine zipper, and then noncovalently bound to the protein, thus making it system particularly useful for targeting studies.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Biological Transport
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Cell-Penetrating Peptides / chemistry
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Cell-Penetrating Peptides / metabolism*
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Gene Products, tat / chemistry
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Gene Products, tat / metabolism
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Green Fluorescent Proteins / chemistry
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Green Fluorescent Proteins / metabolism*
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HeLa Cells
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Humans
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Leucine Zippers*
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Models, Molecular
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Molecular Sequence Data
Substances
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Cell-Penetrating Peptides
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Gene Products, tat
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Green Fluorescent Proteins