Cardiac troponin-T and CK-MB (mass) levels in cardiac and non cardiac disease

G Chinnapu Reddy; G Kusumanjali; A H R Sharada; Pragna Rao

doi:10.1007/BF02894263

Cardiac troponin-T and CK-MB (mass) levels in cardiac and non cardiac disease

Indian J Clin Biochem. 2004 Jul;19(2):91-4. doi: 10.1007/BF02894263.

Authors

G Chinnapu Reddy¹, G Kusumanjali, A H R Sharada, Pragna Rao

Affiliation

¹ Kamineni Institute of Medical Sciences, Narketpally, 508 254 Nalgonda District, Andhra Pradesh.

Abstract

Serum cardiac troponin T (cTnT) and CKMB (mass) were analysed in three groups of patients. The first group (n=32) were patients with acute coronary syndromes including myocardial infarction. The second group (n=35)were patients with hypertension. The third group (n=24) were patients who had succumbed to non cardiac diseases. In all 3 groups, cardiac troponin T was elevated when compared with controls (p<0.001). However, CKMB elevation was not significant in all groups. CKMB levels correlated well with troponin T levels only when CKMB was greater than 50 ng/ml (r=1.00). Small elevations of troponin T identifies minimal cardiac necrosis and patients can benefit from early invasive therapy.

Keywords: CK-MB (mass); Troponin-T; acute coronary syndromes; hypertension.