Pictorial review of in vivo human brain: from anatomy to molecular imaging

Zang-Hee Cho; Chang-Ki Kang; Young-Don Son; Sang-Han Choi; Yeong-Bae Lee; Sun Ha Paek; Chan-Woong Park; Je-Guen Chi; Fernando Calamante; Meng Law; Young-Bo Kim

doi:10.1016/j.wneu.2012.10.020

Pictorial review of in vivo human brain: from anatomy to molecular imaging

World Neurosurg. 2014 Jul-Aug;82(1-2):72-95. doi: 10.1016/j.wneu.2012.10.020. Epub 2012 Oct 24.

Authors

Affiliations

¹ Neuroscience Research Institute, School of Medicine, Gachon University, Incheon, Korea. Electronic address: zcho@gachon.ac.kr.
² Neuroscience Research Institute, School of Medicine, Gachon University, Incheon, Korea.
³ Department of Neurology, Gachon University Gil Medical Center, School of Medicine, Gachon University, Incheon, Korea.
⁴ Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
⁵ Neuroscience Research Institute, School of Medicine, Gachon University, Incheon, Korea; Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
⁶ Neuroscience Research Institute, School of Medicine, Gachon University, Incheon, Korea; Department of Pharmacology, Seoul National University College of Medicine, Seoul, Korea.
⁷ Brain Research Institute, Victoria, Queensland, Australia.
⁸ Radiology and Neurological Surgery, Keck Medical Center, University of Southern California, Los Angeles, California, USA.
⁹ Neuroscience Research Institute, School of Medicine, Gachon University, Incheon, Korea; Department of Neurosurgery, School of Medicine, Gachon University, Incheon, Korea.

PMID: 23103260
DOI: 10.1016/j.wneu.2012.10.020

Abstract

Recent advances in neuroimaging demonstrated many markedly improved images hitherto unavailable, specifically the areas that lie deep in the brain. The anatomic images of the deep brain structure taken in vivo using 7.0 T magnetic resonance imaging (MRI) and the molecular images using high resolution research tomography positron emission tomography, as well as the fusion images using state-of-art neuroimaging techniques can contribute to the noninvasive treatment of neurologic and psychiatric diseases. We present a pictorial review with selected brain images obtained from 7.0 T MRI, and the images of brain metabolic function accompanied with high resolution anatomic information obtained using the positron emission tomography-MRI fusion technique. In addition, we present some recent results of the cerebral microvasculature and diffusion tractography imaging for the deep brain areas acquired with 7.0 T MRI.

Keywords: Anatomy; High field; Imaging; MRI; Molecular.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Brain / anatomy & histology*
Brain / pathology
Cerebral Angiography
Diffusion Tensor Imaging
Humans
Magnetic Resonance Angiography
Microcirculation / physiology
Molecular Imaging / methods*
Neuroimaging / methods*
Stroke / diagnosis
Stroke / pathology