Detection of Clostridium perfringens type C in pig herds following disease outbreak and subsequent vaccination

Vet Rec. 2012 Nov 17;171(20):503. doi: 10.1136/vr.101052. Epub 2012 Oct 25.

Abstract

Immunisation of sows using Clostridium perfringens type C toxoid vaccines is recommended to prevent necrotising enteritis (NE) on pig breeding farms. Absence of disease, however, oftentimes leads to the false assumption of pathogens being eradicated. The prevalence of C perfringens type C was determined by PCR in faecal samples of piglets and sows in three Swiss pig breeding farms two to four years after implementation of a vaccination programme following disease outbreaks. C perfringens type C could still be detected several years after an outbreak despite absence of NE. In-herd prevalence of the pathogens varied significantly between the farms and was also lower compared with a farm which experienced a recent outbreak. In conclusion, C perfringens type C can be detected on once-affected farms, even in the absence of NE for several years.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn
  • Bacterial Vaccines / administration & dosage*
  • Bacterial Vaccines / immunology
  • Clostridium Infections / epidemiology
  • Clostridium Infections / microbiology
  • Clostridium Infections / prevention & control
  • Clostridium Infections / veterinary*
  • Clostridium perfringens / isolation & purification*
  • Disease Outbreaks / prevention & control
  • Disease Outbreaks / veterinary*
  • Enteritis / epidemiology
  • Enteritis / microbiology
  • Enteritis / prevention & control
  • Enteritis / veterinary
  • Enterotoxins / genetics
  • Feces / microbiology
  • Female
  • Male
  • Necrosis / epidemiology
  • Necrosis / microbiology
  • Necrosis / prevention & control
  • Necrosis / veterinary
  • Prevalence
  • Swine
  • Swine Diseases / epidemiology*
  • Swine Diseases / microbiology
  • Swine Diseases / prevention & control

Substances

  • Bacterial Vaccines
  • Enterotoxins