Early onset multiple sclerosis: a review for nurse practitioners

J Pediatr Health Care. 2012 Nov-Dec;26(6):399-408. doi: 10.1016/j.pedhc.2011.02.006. Epub 2011 Apr 20.

Abstract

Research demonstrates that 3.5% to 5% of persons with multiple sclerosis (MS) present before the age of 18 years. MS can present in early childhood through adolescence and must be considered as a differential diagnosis in patients with motor impairment, sensory changes, and cognitive disability. The diagnosis of early-onset MS is based on findings from a complete history and physical examination along with brain and spine imaging. The purpose of this article is to review recent literature on early-onset MS and offer suggestions or clinical practice in the identification and management of patients with this debilitating disease.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Age of Onset
  • Anti-Inflammatory Agents / therapeutic use
  • Anticonvulsants / therapeutic use
  • Antiparkinson Agents / therapeutic use
  • Brain / pathology
  • Central Nervous System Stimulants / therapeutic use
  • Child
  • Disease Progression
  • Fatigue / nursing
  • Female
  • Guidelines as Topic
  • Humans
  • Incidence
  • Magnetic Resonance Imaging
  • Male
  • Multiple Sclerosis / diagnosis
  • Multiple Sclerosis / nursing*
  • Multiple Sclerosis / therapy
  • Muscle Weakness / diagnosis
  • Muscle Weakness / nursing*
  • Muscle Weakness / therapy
  • Nurse Practitioners
  • Optic Neuritis / diagnosis
  • Optic Neuritis / nursing*
  • Optic Neuritis / therapy

Substances

  • Anti-Inflammatory Agents
  • Anticonvulsants
  • Antiparkinson Agents
  • Central Nervous System Stimulants