Glutaminolysis feeds mTORC1

Cell Cycle. 2012 Nov 15;11(22):4107-8. doi: 10.4161/cc.22632. Epub 2012 Oct 24.
No abstract available

Publication types

  • Editorial

MeSH terms

  • Animals
  • Autophagy
  • Gene Knock-In Techniques
  • Glutamine / metabolism*
  • Glutarates / metabolism
  • Humans
  • Isocitrate Dehydrogenase / genetics
  • Isocitrate Dehydrogenase / metabolism
  • Ketoglutaric Acids / metabolism
  • Mechanistic Target of Rapamycin Complex 1
  • Mice
  • Multiprotein Complexes / genetics
  • Multiprotein Complexes / metabolism*
  • Mutation
  • TOR Serine-Threonine Kinases / genetics
  • TOR Serine-Threonine Kinases / metabolism*

Substances

  • Glutarates
  • Ketoglutaric Acids
  • Multiprotein Complexes
  • Glutamine
  • alpha-hydroxyglutarate
  • Isocitrate Dehydrogenase
  • IDH1 protein, human
  • Mechanistic Target of Rapamycin Complex 1
  • TOR Serine-Threonine Kinases