Cutaneous mastocytosis extending beyond a radiotherapy site: a form of radiodermatitis or a neoplastic phenomenon?

Australas J Dermatol. 2013 Nov;54(4):e85-7. doi: 10.1111/j.1440-0960.2012.00961.x. Epub 2012 Oct 25.

Abstract

Ionising radiation is often used as an adjuvant in the management of breast cancer. Acute and chronic skin changes are well recognised complications associated with its use. We demonstrate a rare clinical presentation of cutaneous mastocytosis that occurred at the site of radiotherapy and then extended beyond this boundary, and ask whether this can be treated as a localised side effect of radiotherapy or whether the potential for systemic mastocytosis needs to be excluded.

Keywords: cutaneous mastocytosis; radiodermatitis; systemic mastocytosis.

Publication types

  • Case Reports

MeSH terms

  • Breast Neoplasms / radiotherapy*
  • Breast Neoplasms / surgery
  • Carcinoma, Ductal, Breast / radiotherapy*
  • Carcinoma, Ductal, Breast / surgery
  • Female
  • Histamine Antagonists / therapeutic use
  • Humans
  • Middle Aged
  • Radiodermatitis / drug therapy
  • Radiodermatitis / etiology
  • Radiodermatitis / pathology*
  • Radiotherapy, Adjuvant / adverse effects
  • Urticaria Pigmentosa / drug therapy
  • Urticaria Pigmentosa / etiology
  • Urticaria Pigmentosa / pathology*

Substances

  • Histamine Antagonists