Synthesis and photophysical study of 2'-deoxyuridines labeled with fluorene derivatives

Hyun Yi Cho; Sang Keun Woo; Gil Tae Hwang

doi:10.3390/molecules171012061

Synthesis and photophysical study of 2'-deoxyuridines labeled with fluorene derivatives

Molecules. 2012 Oct 15;17(10):12061-71. doi: 10.3390/molecules171012061.

Authors

Hyun Yi Cho¹, Sang Keun Woo, Gil Tae Hwang

Affiliation

¹ Department of Chemistry and Green-Nano Materials Research Center, Kyungpook National University, Daegu 702-701, Korea.

Abstract

We examined microenvironment-sensitive fluorescent 2'-deoxyuridines labeled with fluorene derivatives that exhibited solvent-dependent photophysical properties. The high sensitivity of the fluorescence shift and the nucleoside intensity dependence on solvent polarity provided information useful for estimating the polarity of the environment surrounding the fluorescent nucleoside.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Deoxyuridine / chemical synthesis*
Deoxyuridine / chemistry
Fluorenes / chemistry*
Fluorescent Dyes / chemistry*
Solvents
Spectrometry, Fluorescence
Staining and Labeling

Substances

Fluorenes
Fluorescent Dyes
Solvents
fluorene
Deoxyuridine