[Rizatriptan-induced liver toxicity. Report of a case]

Alberto Fernandez-Atutxa; Mercedes Vergara; Montserrat Gil; Blai Dalmau; Mireia Miquel; Jordi Sanchez-Delgado; Meritxell Casas

doi:10.1016/j.gastrohep.2012.07.010

[Rizatriptan-induced liver toxicity. Report of a case]

Gastroenterol Hepatol. 2013 Apr;36(4):261-3. doi: 10.1016/j.gastrohep.2012.07.010. Epub 2012 Oct 16.

[Article in Spanish]

Authors

Alberto Fernandez-Atutxa¹, Mercedes Vergara, Montserrat Gil, Blai Dalmau, Mireia Miquel, Jordi Sanchez-Delgado, Meritxell Casas

Affiliation

¹ Servicio de Digestivo, Corporación Sanitaria Parc Taulí, Universidad Autónoma de Barcelona, España. afernandeza@tauli.cat

PMID: 23084593
DOI: 10.1016/j.gastrohep.2012.07.010

Abstract

Triptans are a class of drugs with proven efficacy in the acute treatment of migraine headache. The first component of these drugs was sumatriptan, with various derivatives subsequently emerging. Until now, there has only been one reported case of liver toxicity with zolmitriptan. We now present a case of hepatotoxicity related to another drug in this group: rizatriptan.

Publication types

Case Reports

MeSH terms

Adolescent
Chemical and Drug Induced Liver Injury / etiology*
Female
Humans
Immune Complex Diseases
Jaundice, Obstructive / chemically induced
Migraine Disorders / drug therapy
Serotonin Receptor Agonists / adverse effects*
Serotonin Receptor Agonists / therapeutic use
Time Factors
Triazoles / adverse effects*
Triazoles / therapeutic use
Tryptamines / adverse effects*
Tryptamines / therapeutic use

Substances

Serotonin Receptor Agonists
Triazoles
Tryptamines
rizatriptan