Congenital cataract surgery with intracameral triamcinolone: pre- and postoperative central corneal thickness and intraocular pressure

J AAPOS. 2012 Oct;16(5):441-4. doi: 10.1016/j.jaapos.2012.06.005.

Abstract

Purpose: To evaluate the change in intraocular pressure (IOP) and central corneal thickness (CCT) of children who underwent congenital cataract surgery with injection of triamcinolone acetonide into the anterior chamber at the end of the procedure.

Methods: Fifty-three eyes of 34 children <2 years of age who underwent congenital cataract surgery with injection of 1.2 mg/0.03 mL of preservative-free triamcinolone acetonide into the anterior chamber at the end of the procedure were included in this study. IOP and CCT were measured preoperatively and at a mean of 2 and 12 months' follow-up.

Results: The mean IOP was 8.7 ± 0.4 mm Hg preoperatively, 8.4 ± 0.6 mm Hg at the 2-month follow-up, and 8.1 ± 0.3 mm Hg at the 12-month follow-up. The mean CCT was 562 ± 11 μm preoperatively, 563 ± 10 μm at the 2-month follow-up, and 570 ± 10 μm at the 12-month follow-up. There was no significant change in either pre- or postoperative IOP (P = 0.700) or CCT (P = 0.419) over the study period.

Conclusions: Injection of 1.2 mg triamcinolone acetonide at the end of congenital cataract surgery in children <2 years of age did not significantly affect IOP or CCT in the first year after surgery.

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage*
  • Cataract / congenital*
  • Cataract / pathology
  • Cataract / physiopathology
  • Cataract Extraction / methods*
  • Cornea / pathology
  • Corneal Pachymetry / methods
  • Humans
  • Infant
  • Infant, Newborn
  • Injections, Intraocular
  • Intraocular Pressure / drug effects
  • Ophthalmic Solutions / administration & dosage*
  • Postoperative Care / methods
  • Preoperative Care / methods
  • Retrospective Studies
  • Tonometry, Ocular
  • Triamcinolone Acetonide / administration & dosage*

Substances

  • Anti-Inflammatory Agents
  • Ophthalmic Solutions
  • Triamcinolone Acetonide