Glutamate hypothesis of depression and its consequences for antidepressant treatments

Expert Rev Neurother. 2012 Oct;12(10):1169-72. doi: 10.1586/ern.12.96.
No abstract available

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antidepressive Agents / therapeutic use*
  • Brain / drug effects*
  • Brain / metabolism
  • Depression / drug therapy
  • Depression / metabolism
  • Depressive Disorder, Major / drug therapy*
  • Depressive Disorder, Major / metabolism
  • Excitatory Amino Acid Antagonists
  • Glutamic Acid / chemistry
  • Glutamic Acid / physiology*
  • Humans
  • Molecular Targeted Therapy*
  • Nerve Tissue Proteins / antagonists & inhibitors
  • Nerve Tissue Proteins / metabolism
  • Neurons / drug effects*
  • Neurons / metabolism
  • Receptors, Glutamate / chemistry
  • Receptors, Glutamate / metabolism
  • Synaptic Transmission / drug effects*

Substances

  • Antidepressive Agents
  • Excitatory Amino Acid Antagonists
  • Nerve Tissue Proteins
  • Receptors, Glutamate
  • Glutamic Acid