Therapeutic potential of targeting IL-17

Nat Immunol. 2012 Nov;13(11):1022-5. doi: 10.1038/ni.2450.

Abstract

A June 2012 meeting in Dublin, Ireland, showcased advances in the understanding of the role of IL-17 and related cytokines in host immunity and how these cytokines have been successfully targeted for the treatment of autoimmunity.

Publication types

  • Congress
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptive Immunity / drug effects
  • Animals
  • Antibodies / therapeutic use
  • Autoimmune Diseases / immunology
  • Autoimmune Diseases / therapy
  • Autoimmunity / drug effects
  • Bacterial Infections / immunology
  • Bacterial Infections / therapy
  • Humans
  • Immunity, Innate / drug effects
  • Immunologic Factors / therapeutic use*
  • Interleukin-17 / antagonists & inhibitors
  • Interleukin-17 / immunology*
  • Mice
  • Molecular Targeted Therapy*
  • Mycoses / immunology
  • Mycoses / therapy
  • Neoplasms / immunology
  • Neoplasms / therapy
  • Receptors, Interleukin-17 / antagonists & inhibitors
  • Receptors, Interleukin-17 / immunology*
  • Th17 Cells / drug effects
  • Th17 Cells / immunology
  • Virus Diseases / immunology
  • Virus Diseases / therapy

Substances

  • Antibodies
  • Immunologic Factors
  • Interleukin-17
  • Receptors, Interleukin-17