Echinocandin and ethanol lock therapy treatment of fungal catheter infections

Pediatr Infect Dis J. 2013 Mar;32(3):289-91. doi: 10.1097/INF.0b013e3182784867.

Abstract

Ethanol lock therapy has been implemented to prevent infections of central venous catheters as well as to treat infections. Fungal catheter-associated blood stream infections are historically more difficult to treat and have required removal of central venous catheters. We report the largest case series to date, successfully treating 5 of 7 fungal catheter-associated blood stream infections with ethanol lock therapy and systemic echinocandin administration.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / therapeutic use*
  • Catheter-Related Infections / drug therapy*
  • Catheter-Related Infections / prevention & control
  • Catheters / microbiology*
  • Child
  • Child, Preschool
  • Disinfectants / administration & dosage*
  • Disinfection / methods
  • Echinocandins / therapeutic use*
  • Ethanol / administration & dosage*
  • Fungemia / drug therapy*
  • Fungemia / prevention & control
  • Fungi / drug effects
  • Fungi / isolation & purification
  • Humans
  • Infant
  • Treatment Outcome
  • Young Adult

Substances

  • Antifungal Agents
  • Disinfectants
  • Echinocandins
  • Ethanol