Transcription characteristics of the human cytomegalovirus UL13 gene

Arch Virol. 2013 Feb;158(2):473-7. doi: 10.1007/s00705-012-1461-1. Epub 2012 Oct 13.

Abstract

The human cytomegalovirus (HCMV) UL13 gene is located in the unique long (UL) region of its genome. The transcript structure of UL13 gene has not been investigated to date. By using cDNA library screening, northern blot, and rapid amplification of cDNA ends (RACE), the HCMV UL13 gene was demonstrated to be transcribed from the immediate early (IE) to the late (L) phase of infection, and at least one 1602-nt unspliced transcript was identified in the present study from three clinical isolates.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blotting, Northern
  • Cytomegalovirus / genetics*
  • Gene Expression Regulation, Viral*
  • Gene Library
  • Humans
  • Infant
  • Molecular Sequence Data
  • Sequence Analysis, DNA
  • Time Factors
  • Transcription, Genetic*
  • Viral Proteins / biosynthesis*
  • Viral Proteins / genetics*

Substances

  • Viral Proteins

Associated data

  • GENBANK/JN695808
  • GENBANK/JX003609
  • GENBANK/JX003610
  • GENBANK/JX003611
  • GENBANK/JX003612
  • GENBANK/JX003613
  • GENBANK/JX003614
  • GENBANK/JX003615
  • GENBANK/JX003616
  • GENBANK/JX003617