Objective: Improving effects on serum triacylglyceride in women with hypertriacylglycerolemia by soybean beta-conglycinin.
Methods: A placebo-controlled, randomized, double-blind study was conducted in 100 women aged 40-60 with TC > 6.22 mmol/L (or TG > 1.70 mmol/L). The subjects were administered beta-conglycinin 4.6g (high dose) in 8 test tablets and 2.3g(low dose) in 4 test tablets daily for the two test groups and 4 placebo tablets containing no beta-conglycinin for the control group for 12 weeks.
Results: Compared to the control group, serum triacylglycerol in the high dose group was significantly reduced at the 6th week (P < 0.001) and the 12th week (P = 0.001) of the trial. Serum triacylglycerol in the low dose group was reduced at the 6th week (P < 0.001) of the trial.
Conclusion: Soybean beta-conglycinin seemed to have a positive effect of reducing serum triglycerides and improving serum lipids in people with hyperlipidemia.