Abstract
A case of recurrent cytomegalovirus reactivations in a cytomegalovirus-seropositive woman who received allogeneic cord blood transplantation is described. Thirteen months posttransplantation, her CD3(+) T cell count was extremely low whereas natural killer cells represented 66% of her total lymphocytes. She showed defective thymic function that might contribute to the onset of valganciclovir resistance.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Antiviral Agents / pharmacology*
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Cord Blood Stem Cell Transplantation / adverse effects*
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Cytomegalovirus Infections / immunology*
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Cytomegalovirus Infections / virology
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Drug Resistance, Viral*
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Female
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Ganciclovir / pharmacology*
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Humans
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Killer Cells, Natural / immunology
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T-Lymphocyte Subsets / immunology
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Thymus Gland / physiology*
Substances
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Antiviral Agents
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Ganciclovir