Complications of oropharyngeal dysphagia: aspiration pneumonia

Nestle Nutr Inst Workshop Ser. 2012:72:67-76. doi: 10.1159/000339989. Epub 2012 Sep 24.

Abstract

The incidence and prevalence of aspiration pneumonia (AP) are poorly defined. They increase in direct relation with age and underlying diseases. The pathogenesis of AP presumes the contribution of risk factors that alter swallowing function and predispose to the oropharyngeal bacterial colonization. The microbial etiology of AP involves Staphylococcus aureus, Haemophilus influenzae and Streptococcus pneumoniae for community-acquired AP and Gram-negative aerobic bacilli in nosocomial pneumonia. It is worth bearing in mind the relative unimportance of anaerobic bacteria in AP. When we choose the empirical antibiotic treatment, we have to consider some pathogens identified in oropharyngeal flora. Empirical treatment with antianaerobics should only be used in certain patients. According to some known risks factors, the prevention of AP should include measures in order to avoid it.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Infections / complications*
  • Bacterial Infections / drug therapy
  • Cross Infection / drug therapy
  • Cross Infection / etiology
  • Deglutition
  • Deglutition Disorders / complications*
  • Deglutition Disorders / microbiology
  • Humans
  • Pharynx / microbiology*
  • Pneumonia, Aspiration / drug therapy
  • Pneumonia, Aspiration / etiology*
  • Pneumonia, Aspiration / microbiology
  • Respiratory Aspiration / etiology*
  • Risk Factors

Substances

  • Anti-Bacterial Agents