Abstract
This review highlights the potential of natural and semisynthetic ursane-type triterpenoids as candidates for the design of multi-target bioactive compounds, with focus on their anticancer effects. A brief illustration of the biosynthesis, sources, and general biological effects of the main classes of naturally occurring pentacyclic triterpenoids (PTs) are provided.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Antineoplastic Agents / chemical synthesis
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology
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Biological Products* / chemical synthesis
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Biological Products* / chemistry
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Biological Products* / pharmacology
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Drug Screening Assays, Antitumor
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Humans
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Molecular Structure
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Pentacyclic Triterpenes* / chemical synthesis
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Pentacyclic Triterpenes* / chemistry
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Pentacyclic Triterpenes* / pharmacology
Substances
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Antineoplastic Agents
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Biological Products
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Pentacyclic Triterpenes