Antibacterial activity of 4-oxo-(E)-2-hexenal from adults and nymphs of the heteropteran, Dolycoris baccarum (Heteroptera: Pentatomidae)

Biosci Biotechnol Biochem. 2012;76(10):1975-8. doi: 10.1271/bbb.120321. Epub 2012 Oct 7.

Abstract

We identified 4-oxo-(E)-2-hexenal (4-OHE) as a common component of the secretion from both Dolycoris baccarum nymphs (66.5 ± 34.7 µg/bug) and adults (87.4 ± 48.0 µg/bug) by GC/MS. We also found that this compound inhibited the growth of bacteria starting at 10 µg. The stronger antibacterial activity of 4-OHE than that of (E)-2-hexenal and (E)-2-octenal might be explained by the reactivity of α,β-unsaturated aldehydes with nucleophilic molecules.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / isolation & purification
  • Aldehydes / pharmacology*
  • Animals
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology*
  • Bacteria / drug effects
  • Dose-Response Relationship, Drug
  • Heteroptera / chemistry*
  • Nymph / chemistry

Substances

  • 4-oxo-(E)-2-hexenal
  • Aldehydes
  • Anti-Bacterial Agents