Cell type-dependent effects of andrographolide on human cancer cell lines

Life Sci. 2012 Oct 22;91(15-16):751-760. doi: 10.1016/j.lfs.2012.04.009.

Authors

Myra T W Cheung¹, Rajkumar Ramalingam, Kenneth K K Lau, W L Chiang, S K Chiu

Affiliation

¹ Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong.

PMID: 23047020
DOI: 10.1016/j.lfs.2012.04.009

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Andrographis / chemistry
Antineoplastic Agents, Phytogenic / pharmacology*
Carcinoma, Hepatocellular / drug therapy*
Carcinoma, Hepatocellular / metabolism
Cell Cycle Checkpoints / drug effects*
Cell Line, Tumor
Cell Survival / drug effects
Diterpenes / pharmacology*
HeLa Cells
Hep G2 Cells
Humans
Liver Neoplasms / drug therapy*
Liver Neoplasms / metabolism
Mitosis / drug effects
NF-kappa B / metabolism
Neoplasms / drug therapy
Neoplasms / metabolism
Proteome
Proteomics
Tumor Suppressor Protein p53 / metabolism

Substances

Antineoplastic Agents, Phytogenic
Diterpenes
NF-kappa B
Proteome
Tumor Suppressor Protein p53
andrographolide