A versatile and green mechanochemical route for aldehyde-oxime conversions

Christer B Aakeröy; Abhijeet S Sinha; Kanishka N Epa; Christine L Spartz; John Desper

doi:10.1039/c2cc36315a

A versatile and green mechanochemical route for aldehyde-oxime conversions

Chem Commun (Camb). 2012 Nov 28;48(92):11289-91. doi: 10.1039/c2cc36315a.

Authors

Christer B Aakeröy¹, Abhijeet S Sinha, Kanishka N Epa, Christine L Spartz, John Desper

Affiliation

¹ Department of Chemistry, Kansas State University, Manhattan, KS 66506, USA. aakeröy@ksu.edu

PMID: 23042287
DOI: 10.1039/c2cc36315a

Abstract

A robust, facile and solvent-free mechanochemical path for aldehyde-oxime transformations using hydroxylamine and NaOH is explored; the method is suitable for aromatic and aliphatic aldehydes decorated with a range of substituents.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Aldehydes / chemistry*
Crystallography, X-Ray
Green Chemistry Technology
Hydroxylamine / chemistry
Molecular Conformation
Oximes / chemistry*
Sodium Hydroxide / chemistry

Substances

Aldehydes
Oximes
Hydroxylamine
Sodium Hydroxide