Endobronchial ALK+ anaplastic large-cell lymphoma resembling asthma in a 13-year-old girl

J Pediatr Hematol Oncol. 2013 Jan;35(1):e4-6. doi: 10.1097/MPH.0b013e31827076c4.

Abstract

Anaplastic large-cell lymphoma is a rare disease in children, and endobronchial localization is extremely rare in any age group. We report the case of a 13-year-old girl with endobronchial anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma presenting as asthma, and discuss the diagnostic, therapeutic, and clinical implications.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anaplastic Lymphoma Kinase
  • Asthma / diagnosis*
  • Asthma / enzymology
  • Bronchial Neoplasms / diagnosis*
  • Bronchial Neoplasms / enzymology
  • Bronchial Neoplasms / therapy
  • Child
  • Diagnostic Errors
  • Female
  • Gene Rearrangement
  • Humans
  • Immunoenzyme Techniques
  • Lymphoma, Large-Cell, Anaplastic / diagnosis*
  • Lymphoma, Large-Cell, Anaplastic / enzymology
  • Lymphoma, Large-Cell, Anaplastic / therapy
  • Prognosis
  • Receptor Protein-Tyrosine Kinases / genetics
  • Receptor Protein-Tyrosine Kinases / metabolism*

Substances

  • ALK protein, human
  • Anaplastic Lymphoma Kinase
  • Receptor Protein-Tyrosine Kinases