Copper-catalyzed amination of silyl ketene acetals with N-chloroamines

Tomoya Miura; Masao Morimoto; Masahiro Murakami

doi:10.1021/ol302331k

Copper-catalyzed amination of silyl ketene acetals with N-chloroamines

Org Lett. 2012 Oct 19;14(20):5214-7. doi: 10.1021/ol302331k. Epub 2012 Oct 2.

Authors

Tomoya Miura¹, Masao Morimoto, Masahiro Murakami

Affiliation

¹ Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto 615-8510, Japan. tmiura@sbchem.kyoto-u.ac.jp

PMID: 23030410
DOI: 10.1021/ol302331k

Abstract

A copper(I)/2,2'-bipyridyl complex catalyzes an amination reaction of silyl ketene acetals with N-chloroamines, presenting a new preparative method of α-amino esters.