Microwave assisted synthesis of 2,2'-arylene-substituted bis(4H-3,1-benzoxazin-4-one) derivatives using the complex cyanuric chloride/N,N-dimethylformamide

Molecules. 2012 Sep 28;17(10):11607-15. doi: 10.3390/molecules171011607.

Abstract

A new and efficient method has been designed to prepare 2,2'-arylene-substituted bis(4H-3,1-benzoxazin-4-one) derivatives by using the mixture of cyanuric chloride and N,N-dimethylformamide in a microwave-assisted reaction. The method used and presented here has good rate enhancement and excellent yields.

MeSH terms

  • Benzoxazines / chemical synthesis*
  • Benzoxazines / chemistry
  • Dimethylformamide / chemistry*
  • Microwaves*
  • Transition Temperature
  • Triazines / chemistry*
  • ortho-Aminobenzoates / chemistry

Substances

  • Benzoxazines
  • Triazines
  • bis(4H-3,1-benzoxazin-4-one)
  • ortho-Aminobenzoates
  • anthranilic acid
  • cyanuric chloride
  • Dimethylformamide