The initiation time for zebrafish research in Taiwan was around 1996 and experienced eight years (1996-2003) to establish the fundamental base. From 2004 onwards, zebrafish research project and population in Taiwan is exponentially increasing to a total number of 83 independent research laboratories at this moment. Three major research topics of developmental biology, human disease, and biotechnology are conducted by zebrafish community in Taiwan. Up to now, 342 scientific refereed papers have been published by Taiwan researchers. By 2010, two zebrafish stock centers of TZCAS and ZeTH have been established to provide fish resources to zebrafish community. By the fully support of two zebrafish stock centers, attending physicians and experts in the fields of engineering and bioinformatics are working together with zebrafish people and obtained fruitful results in zebrafish researches in recent years.