Urinary calculi increase the risk for adverse pregnancy outcomes: a nationwide study

Acta Obstet Gynecol Scand. 2013 Jan;92(1):69-74. doi: 10.1111/aogs.12016. Epub 2012 Nov 1.

Abstract

Objective: Using two large-scale nationwide population-based data sets, this study aimed to assess the risk of adverse pregnancy outcomes between mothers with and without urinary calculi.

Design: Cross-sectional study.

Setting: Taiwan.

Sample: This study included 3694 women who had live singleton births and received a diagnosis of urinary calculi (UC) in the year prior to their delivery, as well as 18 470 matched women without UC, who were used as a comparison group.

Methods: Conditional logistic regression analyses were performed.

Main outcome measures: Low birthweight, preterm birth, small for gestational age, cesarean section, lower Apgar score and pre-eclampsia/eclampsia.

Results: Women with UC had a higher prevalence of low-birthweight neonates (7.4 vs. 6.0%, p = 0.003), preterm births (9.5 vs. 7.3%, p < 0.001) and cesarean sections (43.1 vs. 35.4%, p < 0.001) than women without UC. After adjusting for potential confounding factors, women with UC were more likely than women without UC to have low-birthweight neonates (odds ratio 1.21, 95% confidence interval 1.05-1.39), preterm birth (odds ratio 1.28, 95% confidence interval 1.13-1.43) and cesarean sections (odds ratio 1.37, 95% confidence interval 1.28-1.48).

Conclusions: There were increased risks for having low-birthweight, preterm infants and for experiencing cesarean section among women with UC in comparison to women without UC.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apgar Score
  • Birth Weight
  • Cesarean Section / statistics & numerical data
  • Cross-Sectional Studies
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Small for Gestational Age
  • Logistic Models
  • Pre-Eclampsia / epidemiology
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Pregnancy Outcome / epidemiology*
  • Premature Birth
  • Propensity Score
  • Retrospective Studies
  • Risk Factors
  • Taiwan / epidemiology
  • Urolithiasis / epidemiology*