Microbial transformations of 6- and 7-methoxyflavones in Aspergillus niger and Penicillium chermesinum cultures

Edyta Kostrzewa-Susłow; Jadwiga Dmochowska-Gładysz; Tomasz Janeczko; Kamila Sroda; Krystyna Michalak; Anna Palko

doi:10.1515/znc-2012-7-809

Microbial transformations of 6- and 7-methoxyflavones in Aspergillus niger and Penicillium chermesinum cultures

Z Naturforsch C J Biosci. 2012 Jul-Aug;67(7-8):411-7. doi: 10.1515/znc-2012-7-809.

Authors

Edyta Kostrzewa-Susłow¹, Jadwiga Dmochowska-Gładysz, Tomasz Janeczko, Kamila Sroda, Krystyna Michalak, Anna Palko

Affiliation

¹ Department of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. ekostrzew@gmail.com

PMID: 23016281
DOI: 10.1515/znc-2012-7-809

Abstract

A detailed study of the biotransformation of 6- and 7-methoxyflavones by four fungal strains (Aspergillus niger strains MB, KB, and SBP; Penicillium chermesinum 113) was carried out. Products of demethylation and also demethylation combined with hydroxylation at C-4' were identified. The biotransformation products were stronger antioxidants than the substrates.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aspergillus niger / metabolism*
Chromatography, High Pressure Liquid
Flavones / metabolism*
Penicillium / metabolism*
Spectrometry, Mass, Electrospray Ionization

Substances

Flavones