Update on pharmacology of antiplatelets, anticoagulants, and thrombolytics

Neurology. 2012 Sep 25;79(13 Suppl 1):S68-76. doi: 10.1212/WNL.0b013e3182695871.

Abstract

Understanding of the pharmacology of thrombolytics, anticoagulants, and antiplatelets is critical to performing safe and effective endovascular therapy for acute ischemic therapy. This is a basic review of the clinical pharmacologic data on the anticoagulants, antiplatelets, and fibrinolytic agents most commonly used in the treatment of stroke and in the neurointerventional suite.

Publication types

  • Review

MeSH terms

  • Animals
  • Anticoagulants / pharmacology*
  • Anticoagulants / therapeutic use
  • Blood Platelets / drug effects
  • Blood Platelets / metabolism
  • Fibrinolytic Agents / pharmacology*
  • Fibrinolytic Agents / therapeutic use
  • Humans
  • Platelet Aggregation Inhibitors / pharmacology*
  • Platelet Aggregation Inhibitors / therapeutic use
  • Stroke / drug therapy*
  • Stroke / metabolism
  • Stroke / pathology
  • Thrombolytic Therapy / methods
  • Thrombolytic Therapy / trends

Substances

  • Anticoagulants
  • Fibrinolytic Agents
  • Platelet Aggregation Inhibitors