Phase response theory extended to nonoscillatory network components

Phys Rev E Stat Nonlin Soft Matter Phys. 2012 May;85(5 Pt 2):056208. doi: 10.1103/PhysRevE.85.056208. Epub 2012 May 14.

Abstract

New tools for analysis of oscillatory networks using phase response theory (PRT) under the assumption of pulsatile coupling have been developed steadily since the 1980s, but none have yet allowed for analysis of mixed systems containing nonoscillatory elements. This caveat has excluded the application of PRT to most real systems, which are often mixed. We show that a recently developed tool, the functional phase resetting curve (fPRC), provides a serendipitous benefit: it allows incorporation of nonoscillatory elements into systems of oscillators where PRT can be applied. We validate this method in a model system of neural oscillators and a biological system, the pyloric network of crustacean decapods.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Decapoda / cytology
  • Models, Neurological
  • Models, Theoretical*
  • Nerve Net / cytology
  • Physical Phenomena*
  • Synapses / metabolism