Association between obesity measured by different parameters and severity of psoriasis

Int J Dermatol. 2013 Feb;52(2):177-81. doi: 10.1111/j.1365-4632.2011.05270.x. Epub 2012 Sep 24.

Abstract

Background: Obesity has been associated with the severity of psoriasis, but this relationship is not completely understood.

Objectives: This study aimed to evaluate associations between the severity of psoriasis and weight excess as determined using a variety of parameters.

Methods: A cross-sectional study was performed in 296 psoriasis patients. Their body mass index (BMI), waist circumference (WC), and waist : hip ratio (WHR) values were compared with results on a psoriasis area severity index (PASI).

Results: The frequency of severe psoriasis was higher in men (P < 0.05). Direct correlations were established between PASI scores and each of BMI (R = 0.0154, P = 0.01), WC (R = 0.207, P = 0.001), and WHR (R = 0.164, P = 0.007).

Conclusions: This study extends previous reports of an association between psoriasis and obesity and shows a direct correlation between obesity as measured according to different parameters and psoriasis severity.

MeSH terms

  • Adult
  • Body Mass Index*
  • Comorbidity
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obesity / epidemiology*
  • Overweight / epidemiology
  • Prevalence
  • Psoriasis / epidemiology*
  • Severity of Illness Index*
  • Sex Distribution
  • Waist Circumference
  • Waist-Hip Ratio