Ligand-gated ion channels: new insights into neurological disorders and ligand recognition

Chem Rev. 2012 Dec 12;112(12):6285-318. doi: 10.1021/cr3000829. Epub 2012 Sep 18.

Authors

Damien Lemoine¹, Ruotian Jiang, Antoine Taly, Thierry Chataigneau, Alexandre Specht, Thomas Grutter

Affiliation

¹ Laboratoire de Biophysicochimie des Récepteurs Canaux, UMR 7199 CNRS, Conception et Application de Molécules Bioactives, Faculté de Pharmacie, Université de Strasbourg , 67400 Illkirch, France.

PMID: 22988962
DOI: 10.1021/cr3000829

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Humans
Ligand-Gated Ion Channels / antagonists & inhibitors
Ligand-Gated Ion Channels / chemistry
Ligand-Gated Ion Channels / metabolism*
Ligands
Models, Molecular
Nervous System Diseases / drug therapy
Nervous System Diseases / metabolism*

Substances

Ligand-Gated Ion Channels
Ligands