Abstract
We describe asymmetric intramolecular Friedel-Crafts alkylations with a DNA-based hybrid catalyst and propose a plausible binding model. This study shows promise for studying relationships between the helical chirality of DNA and enantioselectivity of the chemical reaction.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkylation
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Catalysis
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Copper / chemistry
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DNA / chemistry*
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Models, Molecular
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Molecular Structure
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Organometallic Compounds / chemistry*
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Pyridines / chemistry
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Stereoisomerism
Substances
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4,4'-dimethyl-2,2'-bipyridine
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Organometallic Compounds
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Pyridines
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Copper
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DNA