Abstract
A biological hydrogel was self-assembled via Watson-Crick base pairing of thymine and adenine from functionalized star poly(ethylene glycol). Our work should provide a novel methodology to generate robust injectable scaffolds with tailorable properties for biomedical applications.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Adenine / chemistry
-
Adenine / metabolism*
-
Base Pairing
-
Cell Proliferation
-
Dexamethasone / metabolism
-
Hydrogel, Polyethylene Glycol Dimethacrylate / chemical synthesis
-
Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry
-
Hydrogel, Polyethylene Glycol Dimethacrylate / metabolism*
-
Hydrogen Bonding
-
Insulin / metabolism
-
Molecular Structure
-
Polyethylene Glycols / chemical synthesis
-
Polyethylene Glycols / chemistry
-
Polyethylene Glycols / metabolism*
-
Stem Cells / metabolism
-
Temperature
-
Thymine / chemistry
-
Thymine / metabolism*
-
Vascular Endothelial Growth Factor A / metabolism
Substances
-
Insulin
-
Vascular Endothelial Growth Factor A
-
Hydrogel, Polyethylene Glycol Dimethacrylate
-
Polyethylene Glycols
-
Dexamethasone
-
Adenine
-
Thymine