Hydrogenation of ecdysteroids

Abstract

Catalytic hydrogenation is extensively used in steroid chemistry. The interest in transformations to the steroid skeleton of ecdysteroids has been increasing in the past years. Essential interest in the chemistry of ecdysteroids is caused by the selective reduction of Δ7 bond with the formation of 7,8-dihydro analogues, because this process allows one to obtain modified structures with new biological activity. Catalytic hydrogenation of isolated and conjugated double bonds and functional groups in ecdysteroids derivatives has been considered in review.