Abstract
In the presence of trifluoromethanesulfonic acid (TfOH) or bis(trifluoromethane-sulfonyl)imide (Tf₂NH), iodosobenzene (PhI=O) efficiently promoted the reactions of dicarbonyl compounds as well as monocarbonyl compounds with nitriles to give 2,4-disubstituted and 2,4,5-trisubstituted oxazole in a single step under the mild conditions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chemistry Techniques, Synthetic*
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Hydrocarbons, Fluorinated / chemistry
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Imides / chemistry
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Iodine / chemistry*
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Iodobenzenes / chemistry
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Ketones / chemistry*
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Mesylates / chemistry
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Molecular Structure
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Nitriles / chemistry*
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Oxazoles / chemical synthesis*
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Oxazoles / chemistry*
Substances
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Hydrocarbons, Fluorinated
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Imides
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Iodobenzenes
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Ketones
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Mesylates
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Nitriles
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Oxazoles
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bis(trifluoromethanesulfonyl)imide
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Iodine
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trifluoromethanesulfonic acid
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iodosobenzene