Synthesis of the reported structures for kealiinines B and C

Org Lett. 2012 Sep 21;14(18):4734-7. doi: 10.1021/ol3019242. Epub 2012 Sep 11.

Abstract

Syntheses of the reported structures of kealiinines B and C have been executed. An intermolecular electrophile-induced cyclization of a pendant arene on an ene-guanidine affords the tetracyclic, oxidized naphthimidazole cores.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Alkaloids / chemical synthesis*
  • Alkaloids / chemistry
  • Cyclization
  • Guanidine
  • Molecular Structure
  • Oxidation-Reduction
  • Stereoisomerism

Substances

  • Alkaloids
  • kealiinine B
  • kealiinine C
  • Guanidine