Acute kidney injury due to intravenous bleach injection

J Med Toxicol. 2013 Mar;9(1):71-4. doi: 10.1007/s13181-012-0259-6.

Abstract

Introduction: Sodium hypochlorite is the active ingredient in bleach, a ubiquitous household disinfectant, and has known toxicities depending on route of exposure and amount. Acute kidney injury due to sodium hypochlorite exposure has never been reported. Patients that did develop nephrotoxicity following bleach exposure did so due to development of other risk factors for kidney injury such as volume depletion or sepsis.

Discussion: We report a patient who presented with black urine after parenteral self-administration of a large quantity of bleach. We review the clinical presentation, laboratory and biopsy findings, and outcome as well as discuss possible mechanisms of sodium hypochlorite toxicity and management strategies.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / chemically induced*
  • Acute Kidney Injury / pathology
  • Acute Kidney Injury / therapy
  • Adolescent
  • Bleaching Agents / poisoning*
  • Female
  • Humans
  • Injections, Intravenous
  • Kidney / drug effects*
  • Kidney / pathology
  • Recovery of Function
  • Renal Dialysis
  • Renal Insufficiency / etiology*
  • Renal Insufficiency / pathology
  • Renal Insufficiency / therapy
  • Sodium Hypochlorite / poisoning*
  • Suicide, Attempted
  • Treatment Outcome

Substances

  • Bleaching Agents
  • Sodium Hypochlorite