[Achalasia: role of endoscopic therapy and surgery]

Presse Med. 2013 May;42(5):814-8. doi: 10.1016/j.lpm.2012.06.011. Epub 2012 Sep 5.
[Article in French]

Abstract

Pneumatic dilation of achalasia has a same medium-term efficacy than surgery and is commonly proposed as the first-line treatment. Intra-sphincteric injection of botulinum toxin is reserved for elderly patients with serious comorbidities. Per-endoscopic myotomy is possible but needs to be evaluated by further studies. Laparoscopic Heller's myotomy in first intension is reserved for young patients less than 40 years. Results of Heller's myotomy are not modified by prior endoscopic treatment or by mega-esophagus. Better surgery results are shown in recent and severe achalasia.

Publication types

  • Review

MeSH terms

  • Adult
  • Age Factors
  • Botulinum Toxins, Type A / therapeutic use
  • Dilatation / methods
  • Esophageal Achalasia / surgery
  • Esophageal Achalasia / therapy*
  • Esophageal Perforation / etiology
  • Esophageal Sphincter, Lower / drug effects
  • Esophageal Sphincter, Lower / surgery
  • Esophagoscopy / methods*
  • Esophagus / surgery
  • Female
  • Hematoma / etiology
  • Humans
  • Male
  • Meta-Analysis as Topic
  • Middle Aged
  • Muscle, Smooth / surgery
  • Patient Selection
  • Postoperative Complications / etiology
  • Randomized Controlled Trials as Topic
  • Retrospective Studies
  • Stents
  • Treatment Outcome

Substances

  • Botulinum Toxins, Type A