Subtotal/near-total treatment of vestibular schwannomas

Curr Opin Otolaryngol Head Neck Surg. 2012 Oct;20(5):380-4. doi: 10.1097/MOO.0b013e328357b220.

Abstract

Purpose of review: The review evaluates current literature on subtotal and near-total resection of vestibular schwannomas.

Recent findings: Recent findings suggest that subtotal and near-total resection of vestibular schwannomas can be performed to improve facial nerve outcomes. This is particularly true for large tumors. Whereas postoperative facial nerve function is likely improved by partial resection, recurrence rates are higher, although they vary depending on the extent of resection. If a tumor remnant grows following partial resection, the small-volume remnant can be treated with stereotactic radiation with good tumor control rates.

Summary: Subtotal and near-total resection of vestibular schwannomas is a reasonable surgical paradigm for vestibular schwannomas which cannot be completely removed without injuring the facial nerve. Whereas facial nerve outcomes are more favorable in partial resections, the risk of recurrence increases and is proportional to the volume of residual tumor.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Decompression, Surgical / adverse effects
  • Decompression, Surgical / methods
  • Facial Nerve Injuries / prevention & control
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Monitoring, Physiologic / methods
  • Neoplasm Invasiveness / pathology
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery*
  • Neoplasm Staging
  • Neoplasm, Residual / pathology
  • Neoplasm, Residual / surgery
  • Nerve Regeneration / physiology
  • Neuroma, Acoustic / pathology*
  • Neuroma, Acoustic / surgery*
  • Neurosurgical Procedures / adverse effects
  • Neurosurgical Procedures / methods*
  • Postoperative Complications / physiopathology
  • Postoperative Complications / therapy
  • Radiosurgery / adverse effects
  • Radiosurgery / methods*
  • Risk Assessment
  • Treatment Outcome
  • Tumor Burden